# Missing Profile for Nikon Coolscan 5000ED with Vuescan

**URL:** https://forums.negativelabpro.com/t/missing-profile-for-nikon-coolscan-5000ed-with-vuescan/6969
**Category:** Troubleshooting and Bugs
**Created:** [October 30, 2023, 10:16pm UTC](https://forums.negativelabpro.com/t/missing-profile-for-nikon-coolscan-5000ed-with-vuescan/6969 "2023-10-30T22:16:24Z")
**Posts on this page:** 1
**Showing post:** 5

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### Author: ![roryjacobs](https://yyz1.discourse-cdn.com/flex029/user_avatar/forums.negativelabpro.com/roryjacobs/32/3964_2.png) [@roryjacobs](https://forums.negativelabpro.com/u/roryjacobs)
#### Post date: [October 16, 2025, 8:47am UTC](https://forums.negativelabpro.com/t/missing-profile-for-nikon-coolscan-5000ed-with-vuescan/6969/5 "2025-10-16T08:47:49Z")

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Hi there, this has been the only thing that’s worked for me after years of searching. And WHAT A DIFFERENCE it’s made using the proper profile. I went from thinking Negative Lab Pro was snake oil to actually for the first time seeing the potential of what they sell.

> [@Profile missing on one file but not the other](https://forums.negativelabpro.com/t/profile-missing-on-one-file-but-not-the-other/4541/3):
>
> Hi, If you wanted to share the two files with me at [nate@natephotographic.com](mailto:nate@natephotographic.com), I could take a look. Some possible culprits would be: If one was scanned as a 64bit (instead of 48bit), then the profiles would not work on the 64 bit DNG. This is because the profiles in Lightroom are meant to work on 3 channel DNGs (16 bits in Red, Green, and Blue channels for 48bit total). The profiles will not work on one channel (monochrome) DNGs or 4 channel DNGS (RGB + infrared). If they are from different …

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