Just want to do a bit of a brain dump here as Iāve been on Nikon Scan with my 9000 since Snow Leopard was a new operating system and I guess I always will. My whole film archive is pretty much scanned like
Nikon Color Management: Off
Positive Mode
Equalise colour channels using analogue gain until they each are around 210 or so. (I make film-specific presets so I can get close fast)
A long long time ago I discovered that Nikon ship some fancy craft LUT colour profiles in Nikon Scan and Iāve long felt I could probably somehow leverage these to take advantage of whatever super science magic went into them. Iām sure the internal ānegative modeā on Nikon Scan uses them and that makes the BEST colours but is unfortunately too uncontrollable to ever really use.
Anyway, so all my scans are positive TIFFs with no profile like this. I used ColorPerfect a lot in the past. Iāve made my own positive ICC profiles from scanned pics of ColorChecker targets using LumaRiver and Iāve tried a bunch of āoff the shelf profilesā. For a long time my best bet was to invert in ColorPerfect or NLP and use my LumaRiver profile but it bugged me that this was a little unscientific and SOME colours in some images would be off. It was good in about 95% of cases.
Things I chased for a long time:
- Overall āred hazeā kind of colour casts in inverted images. Not very bad. Fairly subtle. But annoying once noticed
- Hard to get good punchy reds
- Very strong yellows (bright yellow car, daffodils) going green. Weird because any normal yellow looking great
- If I want to test different colour profiles and techniques I find the most challenging subjects are subtle greens and browns of undergrowth like heather or forest floor stuff
- For what itās worth skin tones are meant to be hard but Iāve never really struggled with that one
Recently I revisited doing manual inversions using Photoshop again. Something Iād played around with in the past but not been satisfied with. But these days, Iām finding really my best results and certainly colour, come from manual inversion using the Nikon_R profile and simple inversions and curves. Weirdly better colour.
OK. I know that wasnāt super focussed or specifically helpful. Iād love to get back to NLP because I like a more ādeterministicā workflow thatās more reproducible but just being frank about where I am in case it helps or resonates with anyone else.
Iāve been reading with interest a bunch of the various colour profile and colour theory threads and it strikes me that I donāt know what a āno Nikon Color Managementā TIFF really is. Before Iād assumed that it was like a RAW with the R G and B numbers indicating the sensor readings from each colour channel. But since learning that, e.g. there is no āpureā green visible to a human eye, Iām left wondering if it is really like that in the TIFF or if it is interpreted in an āsRGB-likeā way to āadapted to human vision but without SPECIFIC profileā ā if you know what I mean.
Iāve avoided the NEF output option all this time because it seems badly supported. But I also assumed the unprocessed TIFF was giving me basically the same thing. But maybe not? Frustrating. Because thatās exactly the starting point you want for an inversion, right? Maybe thatās what makes this game so hard! 
Just in case anyone wants to see what kind of colour and style I do (for context on all these remarks) Iāve also had a Flickr for like ages and Iām fairly OCD on Albums so I have a ColorPerfect album, an NLP album, a Manual Inversion album etc in case you want to compare. Iām just āsamagnewā on Flickr Sam Agnew | Flickr
Stay awesome, Nikon Scanner friend!
Sam
P.S. Like 12 years ago I documented my actual raw film scan methodology. Nothing really has changed apart from I now go 1.8 on the gamma instead of 1.0. Again, that was trial and error really Scanning Colour Negative Film 101 | smashandgrabphoto