I did some testing with Silverfast Ai Studio 9 on my Epson V850 scanner and it seems that the output TIFF file when scanning 48 bit with iSRD saved as TIFF looks exactly the same as the 48 bit HDR RAW saved as TIFF. DNG won’t be the same.
I am scanning with settings Holder, Positive, 48bit, iSRD and following Preferences:
Maybe this is useful to some people with the benefit of dust & scratches removal.